NFL Week 1 Odds, Picks, Predictions, and Best Bets

All the Information You Need to Know for the First Games of the 2024 NFL Season

Betting Lines, Game Info, and Expert Picks

The NFL schedule is out, and the spreads are out for Week 1. Here's a look at the odds for all the first games, plus our best bets for the week.

The model enters Week 1 of the 2024 NFL season on an incredible 185-129 run on top-rated NFL picks that dates back to 2017. Anyone who has followed it is up huge.

We've simulated every game 10,000 times and calculated the expected win probability for every team. Based on those simulations, here are our picks for Week 1:

1. Buffalo Bills -7.5 vs. Cincinnati Bengals
2. Philadelphia Eagles -15 vs. Detroit Lions
3. Kansas City Chiefs -4.5 vs. Arizona Cardinals
4. San Francisco 49ers -6.5 vs. Chicago Bears
5. Green Bay Packers -2.5 vs. Minnesota Vikings

We also have a few bold predictions for Week 1:

1. Justin Fields throws for over 300 yards and 2 touchdowns.
2. Christian McCaffrey rushes for over 100 yards and a touchdown.
3. The New Orleans Saints upset the Atlanta Falcons.

Finally, here are some key stats to keep in mind for Week 1:

• The home team is 5-2 against the spread in Week 1 since 2020.
• The favorite is 6-1 against the spread in Week 1 since 2020.
• The over/under is 4-3 in Week 1 since 2020.

Good luck with your NFL betting in Week 1!

Other intriguing NFL matchups for anyone making NFL score predictions include:

• Los Angeles Chargers -3 vs. Las Vegas Raiders
• Baltimore Ravens -7 vs. New York Jets
• Tennessee Titans -5.5 vs. New York Giants
• Cleveland Browns -2.5 vs. Carolina Panthers
• Washington Commanders -1.5 vs. Jacksonville Jaguars